The Tempe Woman's Club began in 1912, the year Arizona became a state. The women built a small clubhouse in 1916 at the corner of Apache and Mill in Tempe. In 1936, they completed the new clubhouse at the corner of 13th and Mill Streets that is still in use today. This building is on the National Register of Historic Sites, and this woman's club is the oldest organized club in the city. Club members have used the facility to support a variety of charities throughout the years, and the building also provided a venue for social and educational programs.

To pay for the building, members served dinners at the Clubhouse for a variety of groups such as the Lions Club, Rotary, Eastern Star and the Arizona State Teacher's College Football Banquet. They also held dinners and parties to raise money for charities, schools had hospitals. Some of the organizations the women supported included the Child Crisis Center; Ladmo's Boy's and Girl's Clubs; Tempe City Library Society; Salvation Army; Meals on Wheels; Tempe Historical Society; and Tempe Beatification. The clubhouse became the center of social and civic activity for many women residing in Tempe whose influence was felt throughout the community.